Arsenal will take on French outfit Rennes while Chelsea face Ukraine’s Dynamo Kiev in the last 16 of the Europa League.
Rennes are 11th in the French league while Kiev are second behind Shakhtar Donetsk in the Ukrainian Premier League.
Arsenal and Chelsea will both play at home in the first leg on 7 March and play the return legs a week later.
Arsenal qualify by beating BATE Borisov 3-1 on Aggregate while Chelsea made light work of Nalmo.
Chelsea won the competition in 2013, while Emery famously guided Sevilla to three consecutive Europa league triumph.
Europa League last-16 draw
Chelsea v Dynamo Kiev
Eintracht Frankfurt v Inter Milan
Dinamo Zagreb v Benfica
Napoli v FC Salzburg
Valencia v FC Krasnodar
Sevilla v Slavia Prague
Arsenal v Rennes
Zenit St Petersburg v Villarreal