Earlier sacked was Senator Uche Ekwunife.
All the senators from Anambra State, including Ekwunife, emerged on the platform of the Peoples Democratic Party.
Those sacked on Friday by the Supreme Court were Senators Stella Oduah and Andy Ubah.
Oduah was a former Minister of Aviation, while Ubah was a former Special Adviser to former President Olusegun Obasanjo on Domestic Affairs.
To replace them, according to the Supreme Court, are Chris Ubah (Anambra South) and Annie Okonkwo (Anambra Central).